If you are ready to slow down the rate and pace of biological aging to look, feel and perform at your best at any age and every stage of life then you’ll want to know about peptide therapies.
While everyone is talking about weight loss peptides right now like semaglutide and tirzepatide, we will unpack those in a separate article. Today, lets look at what is shown in the research to help your system slow down aging and reduce the risk of chronic disease while offering regenerative and health-optimizing benefits.
What are peptides?
Peptides are naturally occurring in the body. They are short chains of amino acids that govern specific actions and signaling in the body, including supporting cellular functions, promoting tissue repair, and regulating hormonal activity.
How can peptides increase longevity?
The field of longevity and clinical solutions to reverse age are centered around the 9 hallmarks of aging. All research and proposed treatments aim to address as many of the 9 components as possible as proven methods to slow down the rate and pace of aging in the tissues, organs and systems of the body. Peptides are signaling molecules that modulate cellular activity. Since many of the hallmarks show aging occurs at a cellular level, peptide therapy can be a targeted solution to promote enhanced cellular function.
What are the best peptides for longevity?
While the list keeps growing, here are our top 5 longevity peptides
1.Epithalon (Epitalon): Epithalon is a synthetic peptide that has shown promise in extending the lifespan of cells and potentially promoting overall longevity. It is shown to be an antioxidant more potent than melatonin reducing reactive oxygen species in the cell, improving mitochondrial function, and suggesting a beneficial effect on reducing senescent cells. Additionally, In vivo, the research data have proved that Epitalon has a regenerating and life-prolonging effect, as well as a positive effect on the hormonal levels, immune responses, and thyroid gland. In vitro, Epitalon helps to prevent the early aging process of cells, and inhibit tumor development in somatic cells.. (1)
2.Thymosin Alpha-1: Thymosin Alpha-1 is a peptide derived from the thymus gland. It has been studied for its immunomodulatory effects and potential anti-aging properties. Thymosin Alpha-1 enhances immune function, reduces inflammation, is shown to activate natural killer cells, promotes tissue repair, and has even shown the ability to restrain tumor growth. By supporting a healthy immune system, it may help improve overall health and potentially contribute to longevity. (2)
3.Human Growth Hormone (HGH) Fragments: HGH fragments, such as HGH Fragment 176-191, are peptide sequences derived from human growth hormone. They have been investigated for their potential anti-aging effects. These peptides are believed to enhance fat metabolism, increase muscle mass, and improve insulin sensitivity. By modulating these factors, they may contribute to overall health and potentially promote longevity. One of the most popular peptides to aid in the natural production of HGH is CJC/Ipamoralin. This combination has been shown that it may promote better sleep, help increase muscle mass, and promote fat loss—all of which may help prevent premature aging.CJC-1295 and Ipamorelin are two distinct peptides that are often used together in a combined regimen to promote growth hormone release and potentially enhance muscle growth, fat loss, and overall well-being.
- CJC-1295: CJC-1295 is a synthetic peptide that acts as a growth hormone-releasing hormone (GHRH) analog. It works by stimulating the pituitary gland to release more growth hormone (GH). By increasing GH levels, CJC-1295 may promote muscle growth, improve recovery, enhance fat metabolism, and potentially have anti-aging effects. One notable variant of CJC-1295 is CJC-1295 DAC, which has an extended half-life due to the addition of a drug affinity complex (DAC), allowing for less frequent dosing.
- Ipamorelin: Ipamorelin is a peptide known as a growth hormone secretagogue. It stimulates the release of GH by binding to specific receptors in the pituitary gland. Similarly to CJC-1295, Ipamorelin can promote muscle growth, aid in fat loss, and potentially enhance recovery. It has a more selective action on GH release, leading to a more natural pulsatile pattern of growth hormone secretion.
When used together, CJC-1295 and Ipamorelin can have a synergistic effect on GH release. (3)
4.BPC-157: is a peptide derived from a protein found in the stomach. It has been studied for its regenerative and healing properties. BPC-157 aids in tissue repair, and regeneration and promotes the formation of blood vessels. These are crucial factors in maintaining vitality as we age..By supporting tissue healing and regeneration, it may contribute to overall well-being and potentially aid in longevity. (4)
5.GHK-Cu: or Gly-His-Lysine-Copper peptide, is a naturally occurring copper complex found within the human body. This peptide plays a vital role in various physiological processes from tissue healing and repair, modulates immune responses, increases collagen, nail, and hair growth, and has strong anti-inflammatory effects making this one of the favorite aesthetic peptides on the market to keep you looking your best. (5)
It’s important to note that while these peptides have shown promise in scientific studies, more research is needed to fully understand their effects on longevity and to establish optimal dosages, safety profiles, and potential side effects.
Want to become trained in peptide therapy? Contact us to get on the VIP registration list. The on-demand class taught by Dr. Kent Holtorf, Dr. Leonard Pastrana, Dr. Stephanie Rimka and Dr. Melissa Petersen will be available October 1st 2023.